STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3584Citrate synthase part 1, authentic frameshift; Energy metabolism; TCA cycle. (342 aa)    
Predicted Functional Partners:
PAE1499
Aconitate hydratase; Energy metabolism; TCA cycle.
 
 0.997
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.995
PAE2648
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis.
  
 0.990
PAE3585
Citrate synthase part 2, authentic frameshift; Energy metabolism; TCA cycle.
 
  
  0.979
PAE1717
Propionate catabolism protein prpD; Central intermediary metabolism; Other.
 
 
 0.976
PAE2743
Fumarate hydratase class II; Energy metabolism; TCA cycle.
  
 0.972
PAE1287
Malate synthase (glcB); Central intermediary metabolism; Other.
  
 0.961
PAE1220
acetyl-CoA C-acetyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.958
PAE1377
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.958
PAE2183
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.958
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.