STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3587Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport. (299 aa)    
Predicted Functional Partners:
PAE3586
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
 0.998
PAE0722
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
 0.994
PAE0723
Ferredoxin like protein; Energy metabolism; Electron transport.
  
 0.972
PAE1378
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.965
PAE2491
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.958
PAE2475
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.955
PAE2070
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.921
PAE2646
Pyruvate dehydrogenase E1 beta subunit; Energy metabolism; Glycolysis/gluconeogenesis.
  
 
 0.732
PAE3227
Glutamate synthase small subunit gltD; Amino acid biosynthesis; Glutamate family.
  
 
 0.718
sucD
succinyl-CoA synthetase alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.712
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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