Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
psmB2Proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (203 aa)    
Predicted Functional Partners:
psmA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.943
psmB1
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
  
 
0.907
PAE2024
Conserved hypothetical protein.
   
 0.882
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
 
 0.779
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
 
 0.779
rpl40e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.769
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
    
 0.754
PAE2117
Thermosome (chaperonin) alpha subunit; Protein fate; Protein folding and stabilization; Belongs to the TCP-1 chaperonin family.
 
 
 0.734
PAE3273
Thermosome (chaperonin) beta subunit; Protein fate; Protein folding and stabilization; Belongs to the TCP-1 chaperonin family.
 
 
 0.726
rpl4
Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 
 0.718
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.