STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctaB2Cytochrome C oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (303 aa)    
Predicted Functional Partners:
PAE1337
Cytochrome C oxidase subunit I /III; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family.
 
 0.993
PAE1338
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 
 0.988
PAE1357
Cytochrome C oxidase subunit I; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family.
 
 0.985
PAE1355
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 
 0.975
PAE0596
Biosynthesis of cofactors, prosthetic groups, and carriers; Other.
    
  0.900
ctaB1
Cytochrome C oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
  
 
0.900
PAE3598
Nitrite reductase (cytochrome C), conjectural; Energy metabolism; Electron transport.
       0.757
PAE3600
Nitrite reductase (cytochrome d1), conjectural; Energy metabolism; Electron transport.
 
     0.594
PAE3601
uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family.
     
 0.575
PAE1651
Isocitrate dehydrogenase; Energy metabolism; TCA cycle.
   
  
 0.571
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.