Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE3600Nitrite reductase (cytochrome d1), conjectural; Energy metabolism; Electron transport. (545 aa)    
Predicted Functional Partners:
PAE3601
uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family.
       0.773
ctaB2
Cytochrome C oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
     0.594
PAE3598
Nitrite reductase (cytochrome C), conjectural; Energy metabolism; Electron transport.
       0.563
PAE0581
Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.
  
     0.498
PAE3644
Hypothetical protein.
  
     0.463
PAE1362
nosD homolog; Energy metabolism; Electron transport.
  
     0.451
PAE3057
P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome.
  
     0.436
PAE3635
Conserved hypothetical protein.
  
     0.436
PAE3169
Conserved protein with 7 CBS domains; Unclassified.
  
     0.434
PAE3492
Hypothetical; Conserved within genome.
  
     0.432
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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