PAE3603 protein (Pyrobaculum aerophilum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAE3603

Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport. (721 aa)

Predicted Functional Partners:

PAE1362

0.653

PAE3611

0.624

PAE1888

0.591

PAE0579

0.579

PAE3604

0.558

PAE0596

0.557

PAE0581

0.515

PAE2147

0.512

PAE1252

0.508

PAE0289

0.494

Your Current Organism:

Pyrobaculum aerophilum

NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
PAE0289	PAE3603	Metallo cofactor biosynthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.494
PAE0579	PAE0581	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	0.803
PAE0579	PAE0596	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.947
PAE0579	PAE3603	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.579
PAE0581	PAE0579	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.803
PAE0581	PAE0596	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.741
PAE0581	PAE1252	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	Conserved hypothetical protein.	0.545
PAE0581	PAE3603	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.515
PAE0596	PAE0579	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.947
PAE0596	PAE0581	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	0.741
PAE0596	PAE3603	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.557
PAE1252	PAE0581	Conserved hypothetical protein.	Heme biosynthesis protein; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin.	0.545
PAE1252	PAE3603	Conserved hypothetical protein.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.508
PAE1362	PAE3603	nosD homolog; Energy metabolism; Electron transport.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.653
PAE1888	PAE2147	Multicopper oxidase; Unclassified.	Conserved hypothetical protein part 1, authentic frameshift.	0.464
PAE1888	PAE3603	Multicopper oxidase; Unclassified.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.591
PAE2147	PAE1888	Conserved hypothetical protein part 1, authentic frameshift.	Multicopper oxidase; Unclassified.	0.464
PAE2147	PAE3603	Conserved hypothetical protein part 1, authentic frameshift.	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	0.512
PAE3603	PAE0289	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	Metallo cofactor biosynthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.494
PAE3603	PAE0579	Nitric oxide reductase, cytochrome b subunit; Energy metabolism; Electron transport.	Biosynthesis of cofactors, prosthetic groups, and carriers; Other.	0.579