Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE3636Conserved protein (gufA); Unclassified. (246 aa)    
Predicted Functional Partners:
sod
Superoxide dismutase (sod); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.604
PAE2715
Transport and binding proteins; Cations.
 
 0.571
PAE3638
Conserved hypothetical protein.
       0.559
PAE3640
Hypothetical protein.
       0.559
PAE1538
Hypothetical protein.
  
    0.549
PAE2751
Cytochrome C-type biogenesis protein (ccdA), conjectural; Energy metabolism; Electron transport.
  
    0.549
PAE3641
Conserved hypothetical protein.
       0.493
PAE2743
Fumarate hydratase class II; Energy metabolism; TCA cycle.
  
    0.444
PAE2701
Conserved hypothetical protein; Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction. Belongs to the Dps family.
 
    0.403
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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