STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3645Aminotransferase, putative; Unclassified. (315 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.559
PAE3643
Hypothetical protein.
       0.523
PAE3644
Hypothetical protein.
       0.523
PAE3320
D-3-phosphoglycerate dehydrogenase (serA); Amino acid biosynthesis; Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.502
PAE2868
Homoserine dehydrogenase; Amino acid biosynthesis; Aspartate family.
  
 
 0.492
PAE2648
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis.
 
 
 0.490
PAE3642
Hypothetical; Conserved within genome.
       0.467
aroD
3-dehydroquinate dehydratase (aroD) / possible chorismate mutase (multidomain protein); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
  
 0.466
PAE2315
Unclassified.
 
 
 0.464
PAE2420
Cystathionine gamma-synthase; Amino acid biosynthesis; Aspartate family.
  
  
 0.463
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.