STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOS47699.1Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.816
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.756
AOS47151.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.610
AOS46817.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.490
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.475
nadD
Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
  0.474
AOS47489.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.470
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.466
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.464
AOS47150.1
Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.464
Your Current Organism:
Actinomyces hongkongensis
NCBI taxonomy Id: 178339
Other names: A. hongkongensis, Actinomyces hongkongensis Woo et al. 2004, CCUG 48484, CIP 107949, DSM 15629, LMG 21939, LMG:21939, strain HKU8
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