STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWU55_1323Cysteine desulfurase; Scaffold_7_24. (382 aa)    
Predicted Functional Partners:
AWU55_2010
Helicase domain-containing protein; Scaffold_19_90.
  
 0.999
AWU55_1324
Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
 
 0.998
tusA
tRNA 2-thiouridine synthesizing protein A; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
   
 0.992
AWU55_959
SirA-like protein; Scaffold_4_11; Belongs to the sulfur carrier protein TusA family.
   
 0.992
nfuA
Thioredoxin; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.990
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.986
AWU55_1322
Iron-sulfur cluster assembly protein; Scaffold_7_23; Belongs to the HesB/IscA family.
 
 
 0.981
AWU55_1130
Adenylyltransferase; Scaffold_5_51.
   
 0.964
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.961
AWU55_1293
BadM/Rrf2 family transcriptional regulator; Scaffold_6_85.
  
 
 0.941
Your Current Organism:
Halomonadaceae bacterium T822
NCBI taxonomy Id: 1783518
Other names: H. bacterium T82-2, Halomonadaceae bacterium T82-2
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