STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWU55_7245-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1247 aa)    
Predicted Functional Partners:
AWU55_1880
Methylenetetrahydrofolate reductase (NADPH); Scaffold_18_16; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.997
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.987
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
 
 0.972
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.971
AWU55_637
Flavodoxin/nitric oxide synthase; Scaffold_2_49.
  
 0.969
AWU55_126
Homoserine dehydrogenase; Scaffold_0_126.
  
 
 0.968
AWU55_2696
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Scaffold_47_37.
  
 
 0.961
AWU55_1055
Aspartate kinase; Scaffold_4_107; Belongs to the aspartokinase family.
  
 
 0.948
AWU55_17
Sarcosine oxidase, subunit alpha; Scaffold_0_17; Belongs to the GcvT family.
  
 
 0.944
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.944
Your Current Organism:
Halomonadaceae bacterium T822
NCBI taxonomy Id: 1783518
Other names: H. bacterium T82-2, Halomonadaceae bacterium T82-2
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