STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWU55_890Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa)    
Predicted Functional Partners:
AWU55_2295
Pyruvate carboxylase subunit B; Scaffold_30_7.
     
 0.879
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
  0.802
AWU55_3027
Hypothetical protein; Scaffold_208_7.
    
 0.695
AWU55_2108
Aldolase; Scaffold_25_29.
 
      0.673
AWU55_724
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.673
AWU55_1167
Arabinose-5-phosphate isomerase; Scaffold_5_88.
    
  0.652
AWU55_889
Glycerophosphoryl diester phosphodiesterase; Scaffold_3_98.
       0.630
AWU55_1077
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Scaffold_4_129.
     
 0.615
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Scaffold_0_92.
     
 0.615
AWU55_653
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Scaffold_2_65.
   
 
  0.598
Your Current Organism:
Halomonadaceae bacterium T822
NCBI taxonomy Id: 1783518
Other names: H. bacterium T82-2, Halomonadaceae bacterium T82-2
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