Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (307 aa)    
Predicted Functional Partners:
AMP21496.1
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.976
AMP21498.1
DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA.
   
 0.972
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.953
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.940
AMP21495.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.937
AMP25742.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.931
AMP21494.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.920
cobB-2
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.911
AMP23957.1
NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.907
AMP23958.1
NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.907
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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