Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP21515.1Hydrogenase assembly protein HypC; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)    
Predicted Functional Partners:
AMP21516.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.991
AMP21517.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.987
AMP25096.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.964
AMP21514.1
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.960
AMP26408.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.945
hypA
Hydrogenase expression protein HupH; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.860
AMP25100.1
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.835
AMP22565.1
Formate hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.699
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.693
AMP21530.1
Cytochrome-c3 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.661
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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