STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP21656.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.927
AMP21655.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.920
AMP23024.1
acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.853
AMP21544.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.846
AMP23491.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.846
whiB-5
Transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.833
whiB-8
Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.833
AMP22315.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.801
AMP22804.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.800
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.782
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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