STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBUrease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. (103 aa)    
Predicted Functional Partners:
ureA
Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
 0.999
ureC
Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.995
AMP21670.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
AMP21677.1
Urease accessory protein UreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.966
AMP21666.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AMP24087.1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.767
AMP25193.1
Carbamoyl-phosphate-synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.755
AMP24086.1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.702
ybeY
Heat-shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
      
 0.583
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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