Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AMP21670.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)    
Predicted Functional Partners:
ureC
Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
AMP21677.1
Urease accessory protein UreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.991
ureB
Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
 
 
 0.982
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 0.977
ureA
Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
  
 
 0.973
AMP21666.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
AMP26306.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
AMP25237.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.579
AMP24143.1
Isoniazid-inducible protein iniA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
AMP24144.1
Isoniazid-inducible protein iniC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.480
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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