Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AMP21671.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (387 aa)    
Predicted Functional Partners:
AMP24727.1
Ornithine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.919
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.900
leuS
leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.760
AMP23287.1
NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.622
AMP25774.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.605
AMP24210.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.602
AMP24211.1
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.602
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.586
AMP21613.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.567
acnA
Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.561
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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