STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (219 aa)    
Predicted Functional Partners:
ureC
Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.986
AMP21677.1
Urease accessory protein UreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
AMP21670.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.977
ureB
Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
  
 0.974
AMP22565.1
Formate hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.968
ureA
Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
  
 0.941
hypA
Hydrogenase expression protein HupH; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.895
AMP21516.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.742
AMP25096.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.742
AMP21515.1
Hydrogenase assembly protein HypC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.693
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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