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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP21690.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)    
Predicted Functional Partners:
AMP21687.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.802
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
    
   0.787
cobB-2
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
    
   0.787
AMP21691.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.768
lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.728
AMP21688.1
Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
AMP21689.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
priA
Phosphoribosyl isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.
    
  0.491
hisE
phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.488
AMP25785.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.444
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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