STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP21690.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)    
Predicted Functional Partners:
AMP21691.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.768
AMP21687.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.765
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
    
   0.710
cobB-2
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
    
   0.710
AMP21688.1
Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.694
lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.678
AMP21689.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
AMP25785.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.444
AMP24231.1
Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.432
AMP22750.1
Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.406
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.