STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP21848.12,3-dihydroxybiphenyl 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)    
Predicted Functional Partners:
AMP21849.1
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.973
AMP21847.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.953
AMP21852.1
Biphenyl 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.815
AMP21851.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.779
mhpA
3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
  
  0.767
AMP25818.1
Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.705
AMP22360.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.687
AMP21928.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.565
AMP21853.1
PucR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.555
nuoI
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.519
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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