Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AMP21893.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)    
Predicted Functional Partners:
AMP21895.1
NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.792
AMP21894.1
Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.762
AMP25827.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.618
AMP21892.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.607
AMP25828.1
NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.545
AMP22527.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.469
AMP23700.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.457
AMP26196.1
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
  
  
 0.444
AMP22118.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.440
AMP21966.1
Recombinase RecB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.412
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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