Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
AMP21915.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)    
Predicted Functional Partners:
AMP22516.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.997
cobB-2
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
   
 0.913
AMP24577.1
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.902
AMP21914.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.879
AMP25838.1
Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.879
AMP25837.1
DoxX subfamily protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.772
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.748
AMP21698.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.743
AMP25470.1
3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
AMP25471.1
enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.727
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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