Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP21917.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (501 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.844
AMP21916.1
Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.795
AMP25838.1
Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.776
AMP21928.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.672
AMP22576.1
DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.669
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.651
AMP22575.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.650
AMP22936.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.650
AMP21918.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.643
AMP24467.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.631
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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