Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tatCPreprotein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (299 aa)    
Predicted Functional Partners:
tatA
Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
 
 0.994
AMP22620.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
AMP25849.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.842
AMP21707.1
Copper oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.712
AMP23153.1
Oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.712
AMP23291.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.638
AMP25029.1
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
 
  
 0.629
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
   
 0.602
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.581
AMP21956.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.566
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (14%) [HD]