Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP21964.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)    
Predicted Functional Partners:
AMP21965.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.875
AMP24292.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.709
AMP23101.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
AMP21963.1
Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.568
AMP21927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
AMP24317.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.489
AMP25799.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.463
AMP24843.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.461
AMP26498.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
rskA
Anti-sigma K factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regu [...]
  
     0.450
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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