Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP25855.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)    
Predicted Functional Partners:
AMP21985.1
L-asparagine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.679
AMP21984.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.579
AMP25445.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.561
AMP22120.1
PucR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
AMP24360.1
3-hydroxyacyl-ACP dehydratase; Functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family.
  
     0.497
AMP24290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family.
  
     0.482
AMP22616.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.476
AMP24362.1
3-hydroxyacyl-ACP dehydratase; Functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family.
  
     0.466
AMP21654.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.460
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (14%) [HD]