Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uppPUDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa)    
Predicted Functional Partners:
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.927
AMP25950.1
UDP-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.916
AMP21990.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.904
AMP21992.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.794
AMP21988.1
Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.780
AMP21989.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.780
AMP25856.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.732
rnj
Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
      0.627
mshC
cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
       0.610
AMP21731.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
     0.581
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (14%) [HD]