STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP22097.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)    
Predicted Functional Partners:
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
       0.872
AMP22098.1
Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.830
AMP22439.1
NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.764
AMP23339.1
NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.690
AMP22096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.688
AMP22099.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
       0.686
AMP22172.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.672
AMP22095.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.671
AMP25887.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.670
AMP21559.1
FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.663
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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