Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP22098.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)    
Predicted Functional Partners:
AMP22097.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.829
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
       0.773
AMP24178.1
Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.733
AMP22095.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.671
AMP22096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.671
AMP22099.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
       0.618
AMP22324.1
Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.515
AMP23034.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.502
AMP23933.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.491
AMP22094.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.490
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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