STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP22101.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)    
Predicted Functional Partners:
AMP22319.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.682
AMP22130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.605
AMP22097.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.585
AMP22102.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.573
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
       0.533
AMP22099.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
       0.533
AMP22103.1
Diacylglycerol O-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the long-chain O-acyltransferase family.
       0.523
AMP21928.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.467
nucS
Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.436
AMP24998.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.414
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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