STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP22111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)    
Predicted Functional Partners:
AMP25445.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.965
AMP22110.1
Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
     0.887
AMP22109.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.872
AMP22107.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.869
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.824
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 
 0.812
AMP22106.1
Acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.797
AMP25880.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.797
AMP22108.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.797
AMP26417.1
Zinc protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
   
 
 0.757
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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