Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP22131.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)    
Predicted Functional Partners:
AMP22132.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.875
AMP22133.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AMP22134.1
Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AMP22130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.743
lgt
Diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.731
AMP21752.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.469
AMP25318.1
Lipid A biosynthesis acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
whiB-4
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.405
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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