htpG protein (Mycobacterium simiae) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

htpG

Heat shock protein 90; Molecular chaperone. Has ATPase activity. (647 aa)

Predicted Functional Partners:

dnaK

0.998

AMP22138.1

0.995

AMP24484.1

0.995

AMP24869.1

0.995

dnaJ

0.994

dnaJ1

0.993

AMP21815.1

0.991

AMP26148.1

0.967

AMP25341.1

0.967

AMP25142.1

0.960

Your Current Organism:

Mycobacterium simiae

NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMP21815.1	AMP22138.1	VC42_02230	VC42_04395	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMP21815.1	AMP24484.1	VC42_02230	VC42_19275	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMP21815.1	AMP24869.1	VC42_02230	VC42_21820	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family.	0.841
AMP21815.1	AMP25341.1	VC42_02230	VC42_24885	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.745
AMP21815.1	AMP26148.1	VC42_02230	VC42_14370	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.745
AMP21815.1	dnaK	VC42_02230	VC42_17230	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.841
AMP21815.1	htpG	VC42_02230	VC42_04775	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.991
AMP22138.1	AMP21815.1	VC42_04395	VC42_02230	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMP22138.1	AMP25341.1	VC42_04395	VC42_24885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.680
AMP22138.1	AMP26148.1	VC42_04395	VC42_14370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.680
AMP22138.1	dnaJ	VC42_04395	VC42_05430	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.982
AMP22138.1	dnaJ1	VC42_04395	VC42_17240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.982
AMP22138.1	htpG	VC42_04395	VC42_04775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.995
AMP24484.1	AMP21815.1	VC42_19275	VC42_02230	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
AMP24484.1	AMP25341.1	VC42_19275	VC42_24885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.680
AMP24484.1	AMP26148.1	VC42_19275	VC42_14370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.680
AMP24484.1	dnaJ	VC42_19275	VC42_05430	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.982
AMP24484.1	dnaJ1	VC42_19275	VC42_17240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.982
AMP24484.1	htpG	VC42_19275	VC42_04775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.995
AMP24869.1	AMP21815.1	VC42_21820	VC42_02230	Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family.	Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841