Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP22265.1Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (130 aa)    
Predicted Functional Partners:
AMP22264.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.872
AMP21803.1
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
   
 0.823
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.802
glyQS
glycine-tRNA synthetase subunit beta; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.751
AMP26189.1
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
   
  
 0.749
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.746
AMP25111.1
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
     0.740
AMP25998.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.739
AMP22826.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.731
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.719
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (22%) [HD]