Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AMP25925.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)    
Predicted Functional Partners:
AMP25119.1
uroporphyrin-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.978
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.971
AMP22297.1
Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.969
AMP24297.1
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.686
AMP22299.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.645
AMP21945.1
precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.538
AMP21942.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
   
 0.515
AMP24082.1
Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.510
AMP24804.1
NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.454
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.440
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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