Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (292 aa)    
Predicted Functional Partners:
AMP24700.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.840
AMP25142.1
Acetoin utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.834
AMP25674.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
   0.813
AMP23192.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.740
AMP24919.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.740
AMP26139.1
LytTR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.729
AMP24638.1
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.725
AMP24522.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.724
AMP22763.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.721
AMP22214.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.711
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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