Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AMP22620.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)    
Predicted Functional Partners:
tatC
Preprotein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
 
 
 0.984
AMP22621.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.954
AMP25967.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.945
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.931
AMP22511.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.753
tatA
Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
     
 0.718
secF
Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
  
 0.691
AMP24575.1
Primosomal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.673
AMP22354.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.650
AMP24176.1
Peptidase M50; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.644
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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