STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP22630.13-methyladenine DNA glycosylase; Constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)    
Predicted Functional Partners:
AMP22527.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.900
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
      0.895
AMP22631.1
Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.872
AMP22633.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
    0.821
AMP22632.1
Glucosyl-3-phosphoglycerate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.819
AMP22634.1
long-chain-acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.750
AMP26143.1
Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.672
AMP22636.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.642
AMP23405.1
Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.634
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.593
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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