Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP22763.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)    
Predicted Functional Partners:
AMP22762.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
kdpA
Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.930
AMP22757.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.928
AMP22758.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.924
kdpC
Potassium ABC transporter ATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
   
 0.906
kdpB
Potassium transporter KtrB; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
   
 0.904
AMP23027.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.900
AMP26172.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.838
AMP23191.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.834
cobB-2
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
   
    0.818
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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