| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMP21955.1 | AMP22952.1 | VC42_03225 | VC42_09600 | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| AMP21955.1 | AMP23705.1 | VC42_03225 | VC42_14315 | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.917 |
| AMP21955.1 | polA | VC42_03225 | VC42_26350 | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.599 |
| AMP21955.1 | recA | VC42_03225 | VC42_24045 | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.900 |
| AMP22818.1 | AMP22952.1 | VC42_08785 | VC42_09600 | Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
| AMP22951.1 | AMP22952.1 | VC42_09595 | VC42_09600 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| AMP22951.1 | AMP22953.1 | VC42_09595 | VC42_09610 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.593 |
| AMP22952.1 | AMP21955.1 | VC42_09600 | VC42_03225 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| AMP22952.1 | AMP22818.1 | VC42_09600 | VC42_08785 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
| AMP22952.1 | AMP22951.1 | VC42_09600 | VC42_09595 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| AMP22952.1 | AMP22953.1 | VC42_09600 | VC42_09610 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.762 |
| AMP22952.1 | AMP23705.1 | VC42_09600 | VC42_14315 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.851 |
| AMP22952.1 | AMP25573.1 | VC42_09600 | VC42_26375 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| AMP22952.1 | ku | VC42_09600 | VC42_09630 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.985 |
| AMP22952.1 | ligA | VC42_09600 | VC42_22330 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.680 |
| AMP22952.1 | polA | VC42_09600 | VC42_26350 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.926 |
| AMP22952.1 | recA | VC42_09600 | VC42_24045 | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.730 |
| AMP22953.1 | AMP22951.1 | VC42_09610 | VC42_09595 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.593 |
| AMP22953.1 | AMP22952.1 | VC42_09610 | VC42_09600 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.762 |
| AMP22953.1 | ku | VC42_09610 | VC42_09630 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.624 |
