STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP26029.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)    
Predicted Functional Partners:
AMP26428.1
Restriction endonuclease subunit S; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.966
AMP22602.1
Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.640
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.632
AMP26028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.546
AMP22976.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.497
AMP21554.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.429
AMP25668.1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.421
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.417
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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