STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP23160.12-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)    
Predicted Functional Partners:
mhpB
3-(2,3-dihydroxyphenyl)propionate dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.996
AMP23352.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.936
AMP23110.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.911
mhpA
3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
 
 
  0.909
AMP26058.1
3-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.877
AMP23156.1
3-alpha-hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.865
AMP23157.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.856
AMP22319.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.834
AMP23155.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.830
AMP23379.1
Extradiol dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.825
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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