Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP23227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)    
Predicted Functional Partners:
purL
Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...]
      0.864
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
      0.851
AMP22749.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.831
rbpA
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.758
AMP22315.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
AMP23480.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.732
AMP22030.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.731
AMP25238.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
AMP25260.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.711
AMP25263.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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