Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP23318.1Trehalose-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)    
Predicted Functional Partners:
AMP24532.1
Trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.999
AMP22916.1
UDP-glucose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.944
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
    
 0.934
AMP24935.1
Glycogen synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.906
AMP22304.1
Glycosyl hydrolase family 15; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.870
AMP23319.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.794
AMP26191.1
Trehalose synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.772
AMP25523.1
Maltooligosyl trehalose synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.764
AMP25522.1
Malto-oligosyltrehalose trehalohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.717
glgE
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB; Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
  
  
 0.713
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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