STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP23443.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)    
Predicted Functional Partners:
AMP23444.1
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.844
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.774
AMP22913.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.686
AMP24158.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.686
AMP23667.1
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.683
AMP26108.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.680
AMP22718.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
AMP25967.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.653
AMP26248.1
Heparin-binding hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.647
AMP25218.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.643
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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