Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
AMP23477.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.849
AMP23705.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.838
AMP23476.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.806
AMP23478.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.752
AMP21955.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.727
AMP22818.1
Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.671
AMP22576.1
DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.502
AMP22575.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.487
AMP22936.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.487
AMP25029.1
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
   
  0.485
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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