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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP26119.1Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.793
AMP23065.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
AMP25444.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.481
AMP22057.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.469
AMP23564.1
Peptidase M1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.453
AMP21544.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.450
AMP23491.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.450
AMP24288.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.427
AMP22646.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.424
AMP24265.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.423
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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