Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP23564.1Peptidase M1; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)    
Predicted Functional Partners:
AMP26130.1
Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.985
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.676
AMP22565.1
Formate hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.668
AMP23287.1
NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.575
AMP25782.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.510
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.462
AMP24838.1
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.445
AMP23563.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.439
AMP23267.1
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.437
AMP23272.1
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.437
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: low (16%) [HD]