Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP23672.1Ribonuclease; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (157 aa)    
Predicted Functional Partners:
AMP23671.1
Nucleoid-structuring protein H-NS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.878
AMP23668.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.725
AMP23670.1
Copper resistance protein CopC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
AMP25772.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.633
deaD
Cold-shock protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 
 0.633
AMP24688.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
    
 
 0.633
AMP23669.1
Nuclear export factor GLE1; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
AMP24259.1
Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.521
AMP23667.1
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.505
nnrE
Membrane protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers [...]
       0.494
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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